Impurity analysis of 2-butynoic acid by ion chromatography–mass spectrometry
Abstract
Small organic acids are widely used within the pharmaceutical industry but can be difficult to analyse. Ion chromatography is a suitable technique for the analysis of these acids but method development can be hindered as mass spectrometry is not often used as a detector; this means that peak tracking and peak purity cannot be performed. The authors report method development for the analysis of 2-butynoic acid, where by using electrospray...
Paper Details
Title
Impurity analysis of 2-butynoic acid by ion chromatography–mass spectrometry
Published Date
Oct 1, 2019
Journal
Volume
1604
Pages
460470 - 460470
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