Inflammation‐induced mammalian target of rapamycin signaling is essential for retina regeneration

GLIA6.20
Volume: 68, Issue: 1, Pages: 111 - 127
Published: Aug 24, 2019
Abstract
Upon retina injury, Müller glia in the zebrafish retina respond by generating multipotent progenitors to repair the retina. However, the complete mechanisms underlying retina regeneration remain elusive. Here we report inflammation‐induced mammalian target of rapamycin (mTOR) signaling in the Müller glia is essential for retina regeneration in adult zebrafish. We show after a stab injury, mTOR is rapidly activated in Müller glia and later Müller...
Paper Details
Title
Inflammation‐induced mammalian target of rapamycin signaling is essential for retina regeneration
Published Date
Aug 24, 2019
Journal
Volume
68
Issue
1
Pages
111 - 127
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