Improved applicability and robustness of fast cryo-electron tomography data acquisition
Abstract
The power of cryo-electron tomography (cryoET) lies in its capability to characterize macromolecules in their cellular context. Structure determination by cryoET, however, is time-consuming compared to single particle approaches. A recent study reported significant acceleration of data acquisition by a fast-incremental single-exposure (FISE) tilt series scheme. Here we improved the method and evaluated its efficiency and performance. We show...
Paper Details
Title
Improved applicability and robustness of fast cryo-electron tomography data acquisition
Published Date
Nov 1, 2019
Volume
208
Issue
2
Pages
107 - 114
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