AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design

Volume: 20, Issue: 1
Published: Aug 15, 2019
Abstract
The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles differing by even a single base pair. Target sites might carry genetic variations that are not distinguishable by sgRNA designing tools based on one reference genome. AlleleAnalyzer is an open-source software that incorporates single-nucleotide variants and short insertions and deletions to design sgRNAs for precisely editing 1 or multiple haplotypes...
Paper Details
Title
AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design
Published Date
Aug 15, 2019
Volume
20
Issue
1
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