The Further Negative Effect of Hyperuricemia on Left Ventricular Structure and Function in Patients with Type 2 Diabetes Mellitus: A Transthoracic 3D Speckle Tracking Imaging Study

Aims: The aims of this study were to explore the left ventricular (LV) structural abnormality and its risk factors in type 2 diabetes mellitus (T2DM) patients with or without hyperuricemia (HU) and to compare their LV function using three-dimensional speckle tracking echocardiography (3DSTE). Methods: Eighty T2DM patients with preserved LV ejection fraction were included, 40 of whom had HU as co-morbidity. Forty age- and gender-matched controls...