Proteogenomics: From next-generation sequencing (NGS) and mass spectrometry-based proteomics to precision medicine
Abstract
One of the best-established area within multi-omics is proteogenomics, whereby the underpinning technologies are next-generation sequencing (NGS) and mass spectrometry (MS). Proteogenomics has contributed significantly to genome (re)-annotation, whereby novel coding sequences (CDS) are identified and confirmed. By incorporating in-silico translated genome variants in protein database, single amino acid variants (SAAV) and splice proteoforms can...
Paper Details
Title
Proteogenomics: From next-generation sequencing (NGS) and mass spectrometry-based proteomics to precision medicine
Published Date
Nov 1, 2019
Journal
Volume
498
Pages
38 - 46
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