An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
Abstract
Anaerobic bacteria represent an overlooked rich source of biological and chemical diversity. Due to the challenge of cultivation and genetic intractability, assessing the capability of their biosynthetic gene clusters (BGCs) for secondary metabolite production requires an efficient heterologous expression system. However, this kind of host system is still unavailable. Here, we use the facultative anaerobe Streptococcus mutans UA159 as a...
Paper Details
Title
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
Published Date
Aug 14, 2019
Journal
Volume
10
Issue
1
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