Geographical and Temporal Variation in the Incidence and Mortality of Hepato–Pancreato–Biliary Primary Malignancies:1990-2017

Background Hepatic, pancreas, and biliary (HPB) cancers pose serious challenges to global health care systems. These malignancies demonstrate great geographical variations with shifting trends over time. The aim of the present study was to determine the recent trends in incidence, prevalence, and mortality of primary HPB malignancies to guide the further development of effective strategies for prevention, screening, and treatment. Methods The...