Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression

Volume: 10, Issue: 1
Published: Aug 9, 2019
Abstract
SIRT1 histone deacetylase acts on many epigenetic and non-epigenetic targets. It is thought that SIRT1 is involved in oocyte maturation; therefore, the importance of the ooplasmic SIRT1 pool for the further fate of mature oocytes has been strongly suggested. We hypothesised that SIRT1 plays the role of a signalling molecule in mature oocytes through selected epigenetic and non-epigenetic regulation.We observed SIRT1 re-localisation in mature...
Paper Details
Title
Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression
Published Date
Aug 9, 2019
Volume
10
Issue
1
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