Strains matter: Success of murine in vitro spermatogenesis is dependent on genetic background
Abstract
The current strategy to preserve fertility of male prepubertal cancer patients consists of cryopreservation of a testicular tissue biopsy containing spermatogonial stem cells (SSCs). While in humans, fertility restoration strategies from prepubertal testicular tissues are still under investigation and have not yet resulted in complete germ cell differentiation, in mice various studies have described production of sperm and offspring through...
Paper Details
Title
Strains matter: Success of murine in vitro spermatogenesis is dependent on genetic background
Published Date
Dec 1, 2019
Journal
Volume
456
Issue
1
Pages
25 - 30
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