The origin, significance and plasticity of the thermoeffector thresholds: Extrapolation between humans and laboratory rodents

In this review, there is an overarching emphasis on the extrapolation of knowledge from one physiological regulator to another, with a particular emphasis on autonomic thermoregulation in humans and rodents. Through mammalian phylogenetics, one finds evidence for the gradual acquisition of an ability to maintain whole-body thermal stability, with discrete autonomic mechanisms arising for the generation, retention and dissipation of thermal...