VEGF-A and blood vessels: a beta cell perspective
Abstract
Reciprocal signalling between the endothelium and the pancreatic epithelium is crucial for coordinated differentiation of the embryonic endocrine and exocrine pancreas. In the adult pancreas, islets depend on their dense capillary network to adequately respond to changes in plasma glucose levels. Vascular changes contribute to the onset and progression of both type 1 and type 2 diabetes. Impaired revascularisation of islets transplanted in...
Paper Details
Title
VEGF-A and blood vessels: a beta cell perspective
Published Date
Aug 14, 2019
Journal
Volume
62
Issue
11
Pages
1961 - 1968
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Notes
History