Statins in the Prevention and Treatment of Heart Failure: a Review of the Evidence

We summarize the best evidence for statins in the prevention and treatment of heart failure. In patients with cardiovascular risk factors or established atherosclerotic cardiovascular disease (but without heart failure), statins reduce the risk of incident heart failure—mainly by preventing myocardial infarction although an additional benefit from reducing myocardial ischemia cannot be excluded. However, in patients with established heart...