Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis
Abstract
Classic studies on hematopoiesis indicate that blood cell numbers are maintained by rare, hard-wired, transplantable stem cells (SCs). Subsequent studies in other organs have implicitly assumed that all SC hierarchies follow the design of the hematopoietic system. Lineage tracing techniques have revolutionized the study of solid tissue SCs. It thus appears that key characteristics of the hematopoietic SC hierarchy (rarity of SCs, specific marker...
Paper Details
Title
Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis
Published Date
Aug 1, 2019
Journal
Volume
25
Issue
2
Pages
174 - 183
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