Circulating Plasma Metabolomic Profiles Differentiate Rodent Models of Pulmonary Hypertension and Idiopathic Pulmonary Arterial Hypertension Patients
Volume: 32, Issue: 11, Pages: 1109 - 1117
Published: Jul 27, 2019
Abstract
Pulmonary arterial hypertension (PAH) is a severe progressive disease with systemic metabolic dysregulation. Monocrotaline (MCT)-induced and hypoxia-induced pulmonary hypertension (PH) rodent models are the most widely used preclinical models, however, whether or not these preclinical models recapitulate metabolomic profiles of PAH patients remain unclear.In this study, a targeted metabolomics panel of 126 small molecule metabolites was...
Paper Details
Title
Circulating Plasma Metabolomic Profiles Differentiate Rodent Models of Pulmonary Hypertension and Idiopathic Pulmonary Arterial Hypertension Patients
Published Date
Jul 27, 2019
Volume
32
Issue
11
Pages
1109 - 1117
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