Microenvironmental Metabolism Regulates Antitumor Immunity
Abstract
Metabolic reprogramming of cancer cells and the tumor microenvironment are emerging as key factors governing tumor growth, metastasis, and response to therapies including immune checkpoint inhibitors. It has been recognized that rapidly proliferating cancer cells, tumor-infiltrating lymphocytes, and vascular endothelial cells compete for oxygen and nutrients. Tumor cells and other cell types in the microenvironment not only compete for...
Paper Details
Title
Microenvironmental Metabolism Regulates Antitumor Immunity
Published Date
Aug 15, 2019
Journal
Volume
79
Issue
16
Pages
4003 - 4008
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Notes
History