The phosphatase PPM1A inhibits triple negative breast cancer growth by blocking cell cycle progression
Abstract
Estrogen receptor (ER)-negative, progesterone receptor (PR)-negative and HER2-negative, or "triple negative," breast cancer (TNBC) is a poor prognosis clinical subtype that occurs more frequently in younger women and is commonly treated with toxic chemotherapy. Effective targeted therapy for TNBC is urgently needed. Our previous studies have identified several kinases critical for TNBC growth. Since phosphatases regulate the function of kinase...
Paper Details
Title
The phosphatase PPM1A inhibits triple negative breast cancer growth by blocking cell cycle progression
Published Date
Jul 26, 2019
Journal
Volume
5
Issue
1
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