Paediatric and young adult manifestations and outcomes of multiple endocrine neoplasia type 1

Context Multiple endocrine neoplasia 1 (MEN 1) is an autosomal dominant disease presenting as hyperplasia and neoplasia of parathyroid, pituitary and enteropancreatic tissues. Over 90% of gene carriers develop phenotypic disease by age 30 years, potentially with onset of asymptomatic disease during childhood and adolescence. Objective To describe the paediatric and young adult manifestations of MEN 1. Design Descriptive retrospective study of...