Serum anti-EIF3A autoantibody as a potential diagnostic marker for hepatocellular carcinoma
Abstract
Tumor-associated autoantibodies are promising diagnostic biomarkers for early detection of tumors. We have screened a novel tumor-associated autoantibody in hepatocellular carcinoma (HCC) model mice. Its target antigen was identified as eukaryotic translation initiation factor 3 subunit A (EIF3A) by proteomic analysis, and the elevated expression of EIF3A in HCC tissues of tumor model mice as well as human patients was shown. Also, its existence...
Paper Details
Title
Serum anti-EIF3A autoantibody as a potential diagnostic marker for hepatocellular carcinoma
Published Date
Jul 30, 2019
Journal
Volume
9
Issue
1
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