Insights into new mechanisms and models of cancer stem cell multidrug resistance
Abstract
The acquisition of genetic alterations, clonal evolution, and the tumor microenvironment promote cancer progression, metastasis and therapy resistance. These events correspond to the establishment of the great phenotypic heterogeneity and plasticity of cancer cells that contribute to tumor progression and resistant disease. Targeting resistant cancers is a major challenge in oncology; however, the underlying processes are not yet fully...
Paper Details
Title
Insights into new mechanisms and models of cancer stem cell multidrug resistance
Published Date
Feb 1, 2020
Journal
Volume
60
Pages
166 - 180
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Notes
History