Recent advances in the engineering and application of streptavidin-like molecules

Streptavidin (SA), and other related proteins, has been isolated from a wide range of organisms, including bacteria, fungi, frogs, fish, and birds. Although their original function is not well understood, they have found an important place in biotechnology based on their unique ability to bind biotin molecules with high affinity and specificity. The SA–biotin interaction is robust and easy to incorporate into different designs, and as such, it...