Serum PD-1 Is Elevated after Pembrolizumab Treatment but Has No Predictive Value
Abstract
Immune-checkpoint blockade (ICB) uses antibody targeting of specific inhibitory receptors and ligands. The major limitations of ICB, such as high cost, limited success rate, and immune-related adverse events (irAE), highlight the need for predictive biomarkers. We analyzed pre-immunotherapy and post-immunotherapy serum samples of 24 patients treated with pembrolizumab for changes in PD-1 and over 1,000 additional protein markers using a...
Paper Details
Title
Serum PD-1 Is Elevated after Pembrolizumab Treatment but Has No Predictive Value
Published Date
Oct 1, 2019
Volume
18
Issue
10
Pages
1844 - 1851
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