A multi-labeled tree dissimilarity measure for comparing “clonal trees” of tumor progression
Abstract
We introduce a new dissimilarity measure between a pair of "clonal trees", each representing the progression and mutational heterogeneity of a tumor sample, constructed by the use of single cell or bulk high throughput sequencing data. In a clonal tree, each vertex represents a specific tumor clone, and is labeled with one or more mutations in a way that each mutation is assigned to the oldest clone that harbors it. Given two clonal trees, our...
Paper Details
Title
A multi-labeled tree dissimilarity measure for comparing “clonal trees” of tumor progression
Published Date
Jul 27, 2019
Volume
14
Issue
1
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