Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice

Volume: 100, Pages: 153955 - 153955
Published: Nov 1, 2019
Abstract
ObjectivesThe activation of brown adipose tissue (BAT) is considered as a promising therapeutic target for obesity. APPL1 (Adaptor protein containing the Pleckstrin homology domain, Phosphotyrosine binding domain and Leucine zipper motif) is an intracellular adaptor protein and its genetic variation is correlated with BMI and body fat distribution in diabetic patients. However, little is known about the roles of APPL1 in BAT...
Paper Details
Title
Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice
Published Date
Nov 1, 2019
Volume
100
Pages
153955 - 153955
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