Reactive oxygen species‐mediated endoplasmic reticulum stress response induces apoptosis ofMycobacterium avium‐infected macrophages by activating regulated IRE1‐dependent decay pathway

Volume: 21, Issue: 12
Published: Aug 16, 2019
Abstract
Mycobacterium avium, a slow-growing nontuberculous mycobacterium, causes fever, diarrhoea, loss of appetite, and weight loss in immunocompromised people. We have proposed that endoplasmic reticulum (ER) stress-mediated apoptosis plays a critical role in removing intracellular mycobacteria. In the present study, we investigated the role of the regulated IRE1-dependent decay (RIDD) pathway in macrophages during M. avium infection based on its role...
Paper Details
Title
Reactive oxygen species‐mediated endoplasmic reticulum stress response induces apoptosis ofMycobacterium avium‐infected macrophages by activating regulated IRE1‐dependent decay pathway
Published Date
Aug 16, 2019
Volume
21
Issue
12
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