Interleukin-11: A Neglected Cytokine With Anti-Atherogenic Properties?

Volume: 287, Pages: e283 - e283
Published: Aug 1, 2019
Abstract
Background and Aims: Interleukin-11 (IL-11) is a stromal cell derived cytokine, highly expressed by smooth muscle cells (SMCs), heart, skin and testis. Beyond its known role in stimulating the maturation of megakaryocytes, it also exerts anti-inflammatory effects in T-cells and macrophages. Our preliminary observations indicated that both high-density lipoproteins (HDL) and sphingosine 1-phosphate (S1P) dose dependently induce IL-11 production...
Paper Details
Title
Interleukin-11: A Neglected Cytokine With Anti-Atherogenic Properties?
Published Date
Aug 1, 2019
Volume
287
Pages
e283 - e283
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