LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair
Abstract
Homologous recombination is a key process for maintaining genome integrity and diversity. In eukaryotes, the nucleosome structure of chromatin inhibits the progression of homologous recombination. The DNA repair and recombination protein RAD54 alters the chromatin structure via nucleosome sliding to enable homology searches. For homologous recombination to progress, appropriate recruitment and dissociation of RAD54 is required at the site of...
Paper Details
Title
LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair
Published Date
Jul 31, 2019
Journal
Volume
181
Issue
2
Pages
499 - 509
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