Lycopene improves methotrexate-induced functional alterations of the Madin–Darby kidney cells in a concentration-dependent manner
Volume: 98, Issue: 2, Pages: 111 - 116
Published: Feb 1, 2020
Abstract
Lycopene is one of the most potent antioxidants among carotenoids due to its ability to quench singlet oxygen and react with free radicals to reduce DNA damage. Methotrexate is widely used in the treatment of several types of cancers and autoimmune diseases. One of the most common side effects of a high-dose of methotrexate is kidney injury. In this study, we evaluated effects of lycopene on the Madin–Darby canine kidney cells (MDCK) treated...
Paper Details
Title
Lycopene improves methotrexate-induced functional alterations of the Madin–Darby kidney cells in a concentration-dependent manner
Published Date
Feb 1, 2020
Volume
98
Issue
2
Pages
111 - 116
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