The MSCRAMM Family of Cell-Wall-Anchored Surface Proteins of Gram-Positive Cocci.

Volume: 27, Issue: 11, Pages: 927 - 941
Published: Nov 1, 2019
Abstract
The microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) are a family of proteins that are defined by the presence of two adjacent IgG-like folded subdomains. These promote binding to ligands by mechanisms that involve major conformational changes exemplified by the binding to fibrinogen by the ‘dock-lock-latch’ mechanism or to collagen by the ‘collagen hug’. Clumping factors A and B are two such MSCRAMMs that have...
Paper Details
Title
The MSCRAMM Family of Cell-Wall-Anchored Surface Proteins of Gram-Positive Cocci.
Published Date
Nov 1, 2019
Volume
27
Issue
11
Pages
927 - 941
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