GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner.

Volume: 203, Issue: 5, Pages: 1288 - 1297
Published: Sep 1, 2019
Abstract
Although guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) constitute the largest cell surface membrane receptor family and transduce thousands of extracellular signals into the cytoplasm, only four kinds of G protein α subunits (Gαs, Gαi/o, Gαq/11, and Gα12/13) are coupled to regulate cAMP or phosphatidylinositol signals. Growing evidence suggests that viruses tend to hijack GPCRs and harness their activated intracellular...
Paper Details
Title
GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner.
Published Date
Sep 1, 2019
Volume
203
Issue
5
Pages
1288 - 1297
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