Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

W K Jacky Lam; Peiyong Jiang; K.C. Allen Chan; Wenlei Peng; Huimin Shang; Macy M. S. Heung; Suk Hang Cheng; Haiqiang Zhang; O Y Olivia Tse; Radha Raghupathy; Rossa W.K. Chiu; Y.M. Dennis Lo

doi:https://doi.org/10.1038/s41467-019-11226-5

doi.org/10.1038/s41467-019-11226-5

Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

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..., Y.M. Dennis Lo

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Nature Communications16.60

Volume: 10, Issue: 1

Published: Jul 22, 2019

Abstract

Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies. Currently, it is not known whether patients with different EBV-associated diseases have different methylation profiles of circulating EBV DNA. Through whole-genome methylation analysis of plasma samples from patients with nasopharyngeal carcinoma (NPC), EBV-associated lymphoma and infectious mononucleosis, we demonstrate that EBV DNA methylation profiles...

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Paper Details

Title

Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

DOI

doi.org/10.1038/s41467-019-11226-5

Published Date

Jul 22, 2019

Journal

Nature Communications

Volume

10

Issue

1

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