Melatonin enhances hydrogen peroxide-induced apoptosis in human dental pulp cells
Abstract
Melatonin, at physiological concentrations, was previously found to inhibit proliferation and promote odontogenic differentiation in human dental pulp cells (hDPCs), but its effect on apoptosis is unclear. Our study aimed to investigate the effect of melatonin on the H2O2-mediated viability reduction and apoptosis in hDPCs. hDPCs were treated with H2O2 (0, 250, 500, 1000 μmol/L), melatonin (0, 10−12, 10−10, 10−8 mol/L), and melatonin with H2O2...
Paper Details
Title
Melatonin enhances hydrogen peroxide-induced apoptosis in human dental pulp cells
Published Date
Dec 1, 2019
Journal
Volume
14
Issue
4
Pages
370 - 377
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