Protective Effects of Lanosterol Synthase Up-Regulation in UV-B-Induced Oxidative Stress
Abstract
UV-B radiation may be an important risk factor in cataracts aetiology. After exposure to UV-B radiation, cells show imbalances in the repair of DNA damage, which induce changes in the levels of certain proteins, including alpha-crystallin, which is the most abundant protein in the lens and crucial for the maintenance of lens transparency. Lanosterol synthase (LSS), an essential rate-limiting enzyme in cholesterol biosynthesis, might play...
Paper Details
Title
Protective Effects of Lanosterol Synthase Up-Regulation in UV-B-Induced Oxidative Stress
Published Date
Aug 29, 2019
Journal
Volume
10
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