A combined experimental and theoretical analysis of the solid-state supramolecular self-assembly of N-(2,4-dichlorophenyl)-1-naphthamide: Synthesis, anticholinesterase potential and molecular docking analysis

In the present report, we describe the synthesis of the amide derivative, N-(2,4-dichlorophenyl)-1-naphthamide, 3, via a facile chemical route. The title compound was isolated in 86% yield. The structure of compound 3 was established using spectroscopic methods and X-ray crystallography. In the crystal structure of 3, supramolecular assembly is dominated by classical N–H⋯O hydrogen bonding and C–Cl … π halogen bonding interactions which were...