Traditional serrated adenoma: an overview of pathology and emphasis on molecular pathogenesis

To provide an overview of the pathology and molecular pathogenesis of traditional serrated adenomas (TSA).Describe the morphology and molecules that play a role in their pathogenesis.These exuberant polypoid lesions are typified by tall cells with deeply eosinophilic cytoplasm, elongated nuclei bearing delicate chromatin, ectopic crypt foci, deep clefting of the lining mucosa and an overall resemblance to small bowel mucosa.Broadly, TSAs arise...