Review paper
UCP 2 gene polymorphisms in obesity and diabetes, and the role of UCP 2 in cancer
Abstract
Mitochondria are the primary sites for ATP synthesis and free radical generation in organisms. Abnormal mitochondrial metabolism contributes to many diseases, including obesity, diabetes and cancer. UCP 2 is an ion/anion transporter located in mitochondrial inner membrane, and has a crucial role in regulating oxidative stress, cellular metabolism, cell proliferation and cell death. Polymorphisms of the UCP 2 gene have been associated with...
Paper Details
Title
Published Date
Aug 1, 2019
Journal
Volume
593
Issue
18
Pages
2525 - 2534
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