A possible role for epigenetic feedback regulation in the dynamics of the epithelial-mesenchymal transition (EMT).

Volume: 16, Issue: 6, Pages: 066004
Published: Sep 6, 2019
Abstract
The epithelial-mesenchymal transition (EMT) often plays a critical role in cancer metastasis and chemoresistance, and decoding its dynamics is crucial to design effective therapeutics. EMT is regulated at multiple levels-transcriptional, translational, protein stability and epigenetics; the mechanisms by which epigenetic regulation can alter the dynamics of EMT remain elusive. Here, to identify the possible effects of epigenetic regulation in...
Paper Details
Title
A possible role for epigenetic feedback regulation in the dynamics of the epithelial-mesenchymal transition (EMT).
Published Date
Sep 6, 2019
Volume
16
Issue
6
Pages
066004
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