Original paper
Versatile protamine nanocapsules to restore miR-145 levels and interfere tumor growth in colorectal cancer cells
Volume: 142, Pages: 449 - 459
Published: Sep 1, 2019
Abstract
MicroRNAs (miRNAs) play a key role on gene expression regulation contributing to cell homeostasis, and they are highly dysregulated in cancer. Consequently, miRNA-based therapies are an attractive approach to develop novel anticancer strategies. The main objective of this work was to explore the full potential of protamine nanocapsules (Pr NCs) to develop an anticancer therapy based on the restoration of oncosuppressor miR-145, downregulated in...
Paper Details
Title
Versatile protamine nanocapsules to restore miR-145 levels and interfere tumor growth in colorectal cancer cells
Published Date
Sep 1, 2019
Volume
142
Pages
449 - 459
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