G protein‐coupled receptor pharmacology—The next generation

G protein-coupled receptors (GPCRs) constitute the largest family of receptors and membrane proteins in the human genome. They are widely expressed and activated by a broad range of ligands including neurotransmitters, hormones, metabolites and ions as well as sensory signals.1, 2 Accordingly, it is not surprising that GPCRs are involved in a very broad variety of physiological functions and are the largest class of drug targets being targeted...