Original paper
Efficient Human Cytomegalovirus Replication in Primary Endothelial Cells Is SOCS3 Dependent
Abstract
In immunocompromised patients, human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality. Suppressor of cytokine signaling (SOCS) proteins are very potent negative regulators of the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathways. We hypothesized that HCMV exploits SOCS1 and/or SOCS3 to its advantage.All experiments were carried out with primary human lung-derived microvascular...
Paper Details
Title
Efficient Human Cytomegalovirus Replication in Primary Endothelial Cells Is SOCS3 Dependent
Published Date
Jan 1, 2019
Journal
Volume
62
Issue
2
Pages
80 - 89
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Notes
History