PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway
Abstract
Unfolded protein response (UPR) is an adaptive mechanism that aims at restoring ER homeostasis under severe environmental stress. Malignant cells are resistant to environmental stress, which is largely due to an activated UPR. However, the molecular mechanisms by which different UPR branches are selectively controlled in tumor cells are not clearly understood. Here, we provide evidence that PRKCSH, previously known as glucosidase II beta...
Paper Details
Title
PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway
Published Date
Jul 18, 2019
Journal
Volume
10
Issue
1
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