Facile development of highly sensitive femtomolar electrochemical DNA biosensor using gold nanoneedle-modified electrode

In this paper, a simple one-step electrochemical method was employed for the deposition of gold nanostructures. Different morphologies (Au-nanorods and Au-nanoneedles) were obtained using different concentrations of gold chloride (HAuCl4·3H2O) solution. The gold nanostructure-modified surface was used for the fabrication of DNA biosensor, which was characterized by cyclic voltammetry and differential pulse voltammetry. The DNA immobilization and...