Insulin Resistance in Patients With Acromegaly
Abstract
Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development of insulin resistance and prediabetes/diabetes, but also in the reduction of lipid accumulation, making acromegaly a unique case of severe insulin resistance in the presence of reduced body fat....
Paper Details
Title
Insulin Resistance in Patients With Acromegaly
Published Date
Jul 30, 2019
Journal
Volume
10
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