Looking for safety but overlooking efficacy: Non-inferiority trials of anti-diabetics

Testing new interventions against placebo when effective treatments are already available is considered unethical [ [1] World Medical Association The Declaration of Helsinki. in: Ethical Principles for Medical Research Involving Human Subjects. 2013https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/Date accessed: April 15, 2019 Google Scholar ] and dangerous for patients...