Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets.

Volume: 10, Issue: 1, Pages: 3163 - 3163
Published: Jul 18, 2019
Abstract
Knowledge of key drivers and therapeutic targets in mucosal melanoma is limited due to the paucity of comprehensive mutation data on this rare tumor type. To better understand the genomic landscape of mucosal melanoma, here we describe whole genome sequencing analysis of 67 tumors and validation of driver gene mutations by exome sequencing of 45 tumors. Tumors have a low point mutation burden and high numbers of structural variants, including...
Paper Details
Title
Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets.
Published Date
Jul 18, 2019
Volume
10
Issue
1
Pages
3163 - 3163
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