An epigenetic predictor of death captures multi-modal measures of brain health

Abstract
Individuals of the same chronological age exhibit disparate rates of biological ageing. Consequently, a number of methodologies have been proposed to determine biological age and primarily exploit variation at the level of DNA methylation (DNAm) – a commonly studied epigenetic mechanism. A novel epigenetic clock, termed ‘DNAm GrimAge’ has outperformed its predecessors in predicting the risk of mortality as well as a number of age-related...
Paper Details
Title
An epigenetic predictor of death captures multi-modal measures of brain health
Published Date
Jul 16, 2019
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