MDM2 dual-color in situ hybridization (DISH) aids the diagnosis of intimal sarcomas
Abstract
Intimal sarcoma is a rare malignant mesenchymal tumor arising from the intima of the great vessels and the heart, and is associated with poor outcomes. As clinico-radiological findings and pathological features are often non-specific, the diagnosis of intimal sarcoma is challenging. Recently, MDM2 amplification was reported to be a characteristic genetic event in this tumor. In the present study, we examined MDM2 status by immunohistochemistry,...
Paper Details
Title
MDM2 dual-color in situ hybridization (DISH) aids the diagnosis of intimal sarcomas
Published Date
Nov 1, 2019
Journal
Volume
43
Pages
107142 - 107142
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History