Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy
Abstract
The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to gain mechanistic insight and identify predictive signatures for personalization. However, many immune monitoring technologies face investigator bias, missing unanticipated cellular responses in limited clinical material. We present here a mass cytometry (CyTOF) workflow for standardized, systems-level biomarker discovery in immunotherapy trials. To...
Paper Details
Title
Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy
Published Date
Jul 1, 2019
Journal
Volume
28
Issue
3
Pages
819 - 831.e4
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