Exosomes regulate neurogenesis and circuit assembly

Volume: 116, Issue: 32, Pages: 16086 - 16094
Published: Aug 6, 2019
Abstract
Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits. We show that exosome treatment increases proliferation in developing neural cultures and in vivo in dentate gyrus of P4 mouse brain. We compared the protein cargo and signaling bioactivity of exosomes released by hiPSC-derived neural cultures lacking...
Paper Details
Title
Exosomes regulate neurogenesis and circuit assembly
Published Date
Aug 6, 2019
Volume
116
Issue
32
Pages
16086 - 16094
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