Comprehensive study on Escherichia coli genomic expression : does position really matter?

As a biorefinery platform host, Escherichia coli has been used extensively for the production of metabolites with commercial interest. Moreover, promoter and terminator databases are readily available as well as a wide amount of expression vectors and numerous gene editing technologies. Together with the ever-reducing cost of synthetic DNA, the range of possibilities in metabolic engineering is expanding even more. Recent advances have secured...